Introduction of a Rabbit Carotid Artery Model for Sonothrombolysis Research

Fusiform aneurysm model in rabbit carotid artery.

AIMS To develop a reproducible and accessible model of elastase-induced fusiform aneurysm in carotid rabbit arteries. METHODS Elastase, at a concentration of 1-30 U, was incubated into the lumen of carotid rabbit arteries. Four weeks later, angiography, histomorphometry, immunohistochemistry and zymography were performed. RESULTS The optimal concentration of elastase in this model was 3 U a...

investigating the feasibility of a proposed model for geometric design of deployable arch structures

deployable scissor type structures are composed of the so-called scissor-like elements (sles), which are connected to each other at an intermediate point through a pivotal connection and allow them to be folded into a compact bundle for storage or transport. several sles are connected to each other in order to form units with regular polygonal plan views. the sides and radii of the polygons are...

Report of a Variation of the Right Common Carotid Artery

Carotid artery is the most important artery that carries the major part of the blood supply to the head and neck. The branching of the common carotid artery usually occurs at the upper edge of the thyroid cartilage. The placement of carotid sinus has also increased its importance in this area. Considering the clinical importance of knowledge about carotid artery variations, this case is reporte...

A Penetrating Pellet Jeopardizing Internal Carotid Artery

Successful microbubble sonothrombolysis without tissue-type plasminogen activator in a rabbit model of acute ischemic stroke.

BACKGROUND AND PURPOSE Microbubbles (MB) combined with ultrasound (US) have been shown to lyse clots without tissue-type plasminogen activator (tPA) both in vitro and in vivo. We evaluated sonothrombolysis with 3 types of MB using a rabbit embolic stroke model. METHODS New Zealand White rabbits (n=74) received internal carotid angiographic embolization of single 3-day-old cylindrical clots (0...